Articles Tagged With:
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The Proton Pump Inhibitor Use and Hypertension Link in Menopausal Women
In a large study, long-term use of proton pump inhibitors in menopausal women was associated with an increased risk of developing hypertension.
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Heat-Related Illnesses in Pediatric Patients
This summer has been hot and, unfortunately, many pediatric patients have sustained heat-related conditions. Providers need to be ready to quickly recognize heat-related illnesses and institute prompt and life-saving care to give each patient the chance for the best outcome. The authors comprehensively review common and life-threatening, heat-related illnesses with an emphasis on evidence-based care.
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Cardiac Arrest in Young Athletes
Sudden cardiac death in athletes is a rare but potentially fatal event where the heart suddenly stops beating because of electrical disturbances or underlying heart conditions during physical activity.
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The Walk ’n Watch Trial: Stroke Recovery Through High-Intensity Walking
An intensive real-life walking protocol, started as soon as possible after acute stroke, resulted in improved overall walking endurance, mobility, balance, and quality of life.
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Clinical and Genetic Reassessment of Patients with Presumed Hereditary Polyneuropathy
This is an observational, cross-sectional study of patients seen at a specialized neuromuscular center with a clinical diagnosis of hereditary polyneuropathy, without a previously identified genetic diagnosis. The goal of this study was to assess the combination of clinical reassessment with updated genetic testing, including whole genome sequencing. Reassessment improved the diagnostic clarification rate in these patients.
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Treatment Window for Lowering Blood Pressure in Acute ICH
Effective treatment for acute intracerebral hemorrhage (ICH) has remained elusive, with inconclusive results from surgical evacuations, as well as blood pressure management. The investigators performed a pooled analysis of four INTERACT trials that studied the effect of aggressive blood pressure lowering in patients with acute ICH. Ultra-early treatment (< 3 hours from onset) may be beneficial, but most patients are not so quickly diagnosed or treated.
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EEG in Patients with Disorders of Consciousness
Abnormal background continuity, ictal-interictal continuum features, and an unreactive electroencephalogram (EEG) background were independently associated with unfavorable outcomes in the overall cohort of patients with acute brain injuries. In addition, an unreactive EEG predicted unfavorable outcomes at six months with high specificity across multiple patient subgroups. However, the sensitivity of unreactive EEG for predicting unfavorable outcomes was low.
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Giant Cell Arteritis Has New Options for Steroid-Sparing Therapy
The SELECT-GCA Study trial of patients with giant cell arteritis found that upadacitinib at 15 mg daily combined with a 26-week glucocorticoid taper showed efficacy superior to placebo treatment with a 52-week glucocorticoid taper. The 15-mg dose of oral upadacitinib added to a shorter steroid treatment regimen was well-tolerated and appeared to be safe, as compared to placebo treatment with a longer period of steroid treatment.
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Most Bioethicists View Social Justice as an Important Part of Ethics Role
Most bioethicists see social justice as central to their work. They address inequities by amplifying vulnerable patients’ voices, examining institutional policies, and advising leadership, ensuring healthcare decisions respect dignity, fairness, and broader social responsibilities.
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Studies Reveal Financial Conflicts Often Are Undisclosed, Raising Ethical Concerns
Physicians frequently fail to disclose financial conflicts of interest, undermining trust and objectivity. Discrepancies in reporting highlight the need for standardized disclosure policies, ethicist guidance, and stronger interventions to mitigate industry influence on medicine.